![]() ![]() It has been shown that fluoride crosses the placenta of rats, but only 0.01% of the amount administered is incorporated in fetal tissue. Pregnancy: Teratogenic Effects: Pregnancy Category B. Other studies conducted in rats demonstrated that lower concentrations of fluoride (5 mg/kg of body weight) did not result in impaired fertility and reproductive capabilities. Adverse effects on reproduction were reported for rats, mice, fox, and cattle exposed to 100 ppm or greater concentrations of fluoride in their diet or drinking water. Potential adverse reproductive effects of fluoride exposure in humans have not been adequately evaluated. Some studies report chromosome damage in rodents, while other studies using similar protocols report negative results. ![]() It has been shown that fluoride ion has potential to induce chromosome aberrations in cultured human and rodent cells at doses much higher than those to which humans are exposed. ![]() Fluoride ion is not mutagenic in standard bacterial systems. Epidemiological data provide no credible evidence for an association between fluoride, either naturally occurring or added to drinking water, and risk of human cancer. In a second study, no carcinogenesis was observed in rats, males or females, treated with fluoride up to 11.3 mg/kg of body weight. Equivocal evidence of carcinogenesis was reported in male rats treated with 2.5 and 4.1 mg/kg of body weight. Carcinogenesis, Mutagenesis, Impairment of Fertility: In a study conducted in rodents, no carcinogenesis was found in male and female mice and female rats treated with fluoride at dose levels ranging from 4.1 to 9.1 mg/kg of body weight. Explore how a whitening mouthwash can accompany your oral care routine and other whitening products to help your pearly whites shine.General: Not for systemic treatment. Protecting your teeth from cavities and decay is the first and most important step to a more beautiful smile. Remember that mouthwashes and mouthrinses do not replace regular brushing and flossing. Your dentist or dental hygienist can determine if you are a good candidate for whitening treatments and recommend the best whitening technique for your situation. Talk to your dental professional about the best way to improve the color of your teeth. Other whitening techniques include toothpaste, whitening strips, over-the-counter gels, take-home trays, and professional whitening treatments. The Scientific World Journal study found that even at-home whitening gels with 10 percent carbamide peroxide worked better than mouthwash to whiten teeth when the gel is applied directly to the tooth. In comparison, the bleaching products used by your dentist contain 25-40 percent. Most whitening mouthwashes contain a two percent concentration of hydrogen peroxide. Whitening mouthwash works best when combined with other at-home and professional teeth whitening treatments, according to Restorative Dentistry & Endodontics. Remember not to swallow! How to Get the Best Teeth Whitening Results Most products will require you to swish the solution around your mouth for 60 seconds twice a day. To get the most out of your whitening mouthwash, follow the instructions on the back of the bottle, and commit to using it long-term. A study in the Scientific World Journal showed that hydrogen peroxide mouthwashes increased teeth whiteness over time but found no significant color changes in the first 56 days. How to Use a Whitening Mouthwashįor a whitening mouthwash to be effective, you need to consistently make it part of your oral care routine. The best whitening mouthwash will include ingredients that do more than whiten your teeth, such as fluoride to strengthen your enamel or cetylpyridinium chloride to kill bacteria that cause plaque and bad breath. You regularly rinse your mouth with the whitening solution to change the color of your teeth. Whitening mouthwash contains a bleaching agent called hydrogen peroxide to help remove surface stains from your teeth.
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